16 Facts About Sean Ekins

Sean Ekins is a scientific leader with over twenty-three years of broad experience in drug discovery.

Sean Ekins was born in Cleethorpes, England, on 2 March 1970 to John Ekins and Elsie May Ekins.

Sean Ekins then earned his HND Science Applied Biology from Nottingham Trent University, graduating in 1991, with a sandwich year at the pharmaceutical company Servier in Fulmer, UK where his interest in drug discovery was established.

Sean Ekins collected drug-drug interaction Ki data for other P450s and generated pharmacophores.

Sean Ekins created test sets to test the models, that were ultimately published.

Sean Ekins published seminal ideas on how such models could be used to profile libraries of compounds for predicted drug-drug interactions.

In late 1998 Sean Ekins joined Pfizer and continued his interest in predicting drug-drug interactions and ADME properties.

In 2011 Sean Ekins Co-Founded Phoenix Nest working on treatments for Sanfilippo Syndrome.

Sean Ekins has carried out independent research and collaborative research on topics including pharmacophores for drug transporters, cheminformatics for predicting immunoassay cross reactivity, models for studying nuclear receptor-ligand co-evolution, computational models for PXR agonists and antagonists as well as analyses of large datasets and crowdsourcing data.

In 2010 Sean Ekins was the co-author of seminal papers around data sharing and making pharmaceutical data more open publishing papers:.

Sean Ekins served on the advisory group for ChemSpider and provided an array of pharmaceutical data sets to the database to make it available to the community.

Sean Ekins has highlighted gaps in TB research, specifically in how cheminformatics and other computational tools could be integrated to improve efficiency and provided examples of how computational methods can be used to assist in screening for compounds active against TB.

In February 2011 Sean Ekins began participating in the MM4TB project as part of Collaborative Drug Discovery.

Sean Ekins co-developed a Wiki with Antony John Williams called Science Mobile Applications launched 21 June 2011.

In 2015, Sean Ekins founded Collaborations Pharmaceuticals to build upon collaborations and projects that came out of applying using machine learning approaches.

Since 2014 Sean Ekins has worked on Ebola drug discovery publishing 19 articles.