18 Facts About Ulcerative colitis

1.

Ulcerative colitis is a long-term condition that results in inflammation and ulcers of the colon and rectum.

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2.

Ulcerative colitis is associated with a generalized inflammatory process that can affect many parts of the body.

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3.

PanUlcerative colitis describes involvement of the entire colon, extending from the rectum to the cecum.

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4.

Ulcerative colitis has a significant association with primary sclerosing cholangitis, a progressive inflammatory disorder of small and large bile ducts.

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5.

Ulcerative colitis is an autoimmune disease characterized by T-cells infiltrating the colon.

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Crohn's disease
6.

Furthermore, it has been suggested that the protective benefit of smoking in ulcerative colitis is due to the hydrogen cyanide from cigarette smoke reacting with hydrogen sulfide to produce the non-toxic isothiocyanate, thereby inhibiting sulfides from interrupting the pathway.

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7.

Best test for diagnosis of ulcerative colitis remains endoscopy, which is examination of the internal surface of the bowel using a flexible camera.

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8.

Endoscopic findings in ulcerative colitis include: erythema, friability of the mucosa, superficial ulceration, and loss of the vascular appearance of the colon.

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9.

Ulcerative colitis is usually continuous from the rectum, with the rectum almost universally being involved.

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10.

Standard treatment for ulcerative colitis depends on the extent of involvement and disease severity.

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11.

Acute severe ulcerative colitis requires hospitalisation, exclusion of infections, and corticosteroids.

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12.

Ulcerative colitis can be treated with a number of medications, including 5-ASA drugs such as sulfasalazine and mesalazine.

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13.

Rectal suppository, foam or liquid enema formulations of 5-ASA are used for Ulcerative colitis affecting the rectum, sigmoid or descending colon, and have been shown to be effective especially when combined with oral treatment.

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14.

Unlike Crohn's disease, ulcerative colitis has a lesser chance of affecting smokers than non-smokers.

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15.

Ulcerative colitis typically requires a more prolonged bacteriotherapy treatment than Clostridium difficile infection to be successful, possibly due to the time needed to heal the ulcerated epithelium.

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16.

The response of ulcerative colitis is potentially very favorable with one study reporting 67.

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17.

People with ulcerative colitis usually have an intermittent course, with periods of disease inactivity alternating with "flares" of disease.

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18.

People with ulcerative colitis are at similar or perhaps slightly increased overall risk of death compared with the background population.

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