|FactSnippet No. 1,656,948|
11 Facts About AB5 toxin
AB5 toxin conducted his research in Calcutta making his discovery in 1959, although it was first purified by Robert Koch in 1883.
|FactSnippet No. 1,656,949|
Cholera AB5 toxin is composed of a protein complex that is secreted by the bacterium Vibrio cholerae.
|FactSnippet No. 1,656,950|
Some symptoms of this AB5 toxin include chronic and widespread watery diarrhea and dehydration that, in some cases, leads to death.
|FactSnippet No. 1,656,951|
Pertussis AB5 toxin is secreted by the gram-negative bacterium, Bordetella pertussis.
|FactSnippet No. 1,656,952|
Shiga AB5 toxin, known as Stx, is a AB5 toxin that is produced by the rod shaped Shigella dysenteriae and Escherichia coli.
|FactSnippet No. 1,656,953|
Some symptoms caused by this AB5 toxin are a decrease in platelet count in the blood or thrombocytopenia, an increase in white blood cell count or leukocytosis, and renal cell damage.
|FactSnippet No. 1,656,954|
Subtilase cytoAB5 toxin A subunit is a protease known to cleave binding immunoglobulin protein, leading to endoplasmic reticulum stress and cell death.
|FactSnippet No. 1,656,955|
Pertussis AB5 toxin is different where its pentameric ring is made up of four different protein components, where one of the components is repeated to form a heteropentamer.
|FactSnippet No. 1,656,956|
Shiga AB5 toxin is brought to the golgi apparatus before being directed to the endoplasmic reticulum for PDI to cleave the disulfide bond.
|FactSnippet No. 1,656,957|
SubAB AB5 toxin has been seen to demonstrate specificity to a binding protein, BiP.
|FactSnippet No. 1,656,958|