14 Facts About Cholera


Cholera occurs as both outbreaks and chronically in certain areas.

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Cholera toxin is an oligomeric complex made up of six protein subunits: a single copy of the A subunit, and five copies of the B subunit, connected by a disulfide bond.

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Cholera is mainly a risk in developing countries in those areas where access to WASH infrastructure is still inadequate.

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Cholera exists as a seasonal disease in many endemic countries, occurring annually mostly during rainy seasons.

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Oral Cholera Vaccine has been recognized as an adjunct tool for prevention and control of cholera.

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Cholera had disappeared from the Americas for most of the 20th century, but it reappeared toward the end of that century, beginning with a severe outbreak in Peru.

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Cholera is not endemic in Europe; all reported cases had a travel history to endemic areas.

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Cholera likely has its origins in the Indian subcontinent as evidenced by its prevalence in the region for centuries.

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Cholera officially became the first reportable disease in the United States due to the significant effects it had on health.

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Cholera is no longer considered a pressing health threat in Europe and North America due to filtering and chlorination of water supplies, but it still strongly affects populations in developing countries.

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Cholera cases are much less frequent in developed countries where governments have helped to establish water sanitation practices and effective medical treatments.

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Cholera morbus is a historical term that was used to refer to gastroenteritis rather than specifically to what is defined as the disease of cholera.

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Cholera's model was not immediately accepted, but it was increasingly seen as plausible as medical microbiology developed over the next 30 years or so.

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Cholera's research led the Lasker Foundation to award him its prize in 1967.

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