14 Facts About Cholera

Cholera occurs as both outbreaks and chronically in certain areas.

Cholera toxin is an oligomeric complex made up of six protein subunits: a single copy of the A subunit, and five copies of the B subunit, connected by a disulfide bond.

Cholera is mainly a risk in developing countries in those areas where access to WASH infrastructure is still inadequate.

Cholera exists as a seasonal disease in many endemic countries, occurring annually mostly during rainy seasons.

Oral Cholera Vaccine has been recognized as an adjunct tool for prevention and control of cholera.

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Cholera had disappeared from the Americas for most of the 20th century, but it reappeared toward the end of that century, beginning with a severe outbreak in Peru.

Cholera is not endemic in Europe; all reported cases had a travel history to endemic areas.

Cholera likely has its origins in the Indian subcontinent as evidenced by its prevalence in the region for centuries.

Cholera officially became the first reportable disease in the United States due to the significant effects it had on health.

Cholera is no longer considered a pressing health threat in Europe and North America due to filtering and chlorination of water supplies, but it still strongly affects populations in developing countries.

Cholera cases are much less frequent in developed countries where governments have helped to establish water sanitation practices and effective medical treatments.

Cholera morbus is a historical term that was used to refer to gastroenteritis rather than specifically to what is defined as the disease of cholera.

Cholera's model was not immediately accepted, but it was increasingly seen as plausible as medical microbiology developed over the next 30 years or so.

Cholera's research led the Lasker Foundation to award him its prize in 1967.