10 Facts About Alnylam


Alnylam was founded in 2002 and is headquartered in Cambridge, Massachusetts.

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In 2002, Alnylam was founded by scientists Phillip Sharp, Paul Schimmel, David Bartel, Thomas Tuschl, and Phillip Zamore, and by investors Christoph Westphal and John Kennedy Clarke; John Maraganore was the founding CEO.

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Alnylam raised $26 million and began trading as ALNY on the Nasdaq stock exchange.

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In 2007, it entered into a nonexclusive alliance with Hoffmann-La Roche, in which Alnylam received $331 million in exchange for access to its technology platform.

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Alnylam entered into a 10-year alliance with Monsanto in 2012, to develop biotech solutions for the farming industry by developing natural molecules for crop protection.

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In July 2013, during a Phase I trial Alnylam demonstrated statistically significant reduction of a protein called transthyretin, or TTR and demonstrated human efficacy with intravenous and subcutaneous modes of administration.

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In 2014, Sanofi Genzyme acquired a 12 percent stake in Alnylam and increased its rights to several of the company's drugs for $700 million.

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In February 2020, Alnylam appointed former Sanofi CEO Olivier Brandicourt to its board of directors.

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Alnylam expects to achieve net profits financially in 2022 or 2023.

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In 2016, Alnylam Pharmaceuticals had 18 potential treatments in various development stages in genetic medicine, cardiometabolic disease and hepatic infectious disease.

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