Cachexia is a complex syndrome associated with an underlying illness, causing ongoing muscle loss that is not entirely reversed with nutritional supplementation.
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10 Facts About Cachexia
2.
Cachexia can improve with treatment of the underlying illness but other treatment approaches have limited benefit.
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3.
Cachexia is associated with increased mortality and poor quality of life.
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4.
Cachexia can be caused by diverse medical conditions, but is most often associated with end-stage cancer, known as cancer cachexia.
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5.
Cachexia can be the result of advanced stages of cystic fibrosis, multiple sclerosis, motor neuron disease, Parkinson's disease, dementia, tuberculosis, multiple system atrophy, mercury poisoning, Crohn's disease, trypanosomiasis, rheumatoid arthritis, and celiac disease as well as other systemic diseases.
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6.
The Cachexia SCOre is another validated score that includes evaluation of body weight loss and composition, inflammation, metabolic disturbances, immunosuppression, physical performance, anorexia, and quality of life.
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7.
Cachexia is distinct from sarcopenia, or age-related muscle loss, although they often co-exist.
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9.
Cachexia contributes to significant loss of function and healthcare utilization.
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10.
Cachexia applied the phrase to the chronic wasting associated with malignancy.
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