15 Facts About Psilocybin

1.

Psilocybin is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi.

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2.

Psilocybin is itself biologically inactive but is quickly converted by the body to psilocin, which has mind-altering effects similar, in some aspects, to those of LSD, mescaline, and DMT.

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3.

Psilocybin is known to strongly influence the subjective experience of the passage of time.

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4.

Psilocybin mushrooms have been and continue to be used in indigenous New World cultures in religious, divinatory, or spiritual contexts.

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5.

Psilocybin mushrooms were ranked as the illicit drug with the lowest harm, corroborating conclusions reached earlier by expert groups in the United Kingdom.

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6.

Psilocybin is rapidly dephosphorylated in the body to psilocin, which is an agonist for several serotonin receptors, which are known as 5-hydroxytryptamine receptors.

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7.

Psilocybin is about 100 times less potent than LSD on a weight per weight basis, and the physiological effects last about half as long.

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8.

Psilocybin is a prodrug that is converted into the pharmacologically active compound psilocin in the body by a dephosphorylation reaction.

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9.

Psilocybin is a tryptamine compound with a chemical structure containing an indole ring linked to an ethylamine substituent.

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10.

Psilocybin is a member of the general class of tryptophan-based compounds that originally functioned as antioxidants in earlier life forms before assuming more complex functions in multicellular organisms, including humans.

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11.

Psilocybin is an alkaloid that is soluble in water, methanol and aqueous ethanol, but insoluble in organic solvents like chloroform and petroleum ether.

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12.

Psilocybin is present in varying concentrations in over 200 species of Basidiomycota mushrooms.

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13.

Psilocybin mushrooms occur on all continents, but the majority of species are found in subtropical humid forests.

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14.

Psilocybin have been found for some individuals to have bare minimal harmful effects and have benefited some individuals that suffer from depression.

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15.

Psilocybin has been tested for its potential for developing prescription drugs to treat drug dependence, anxiety, or mood disorders.

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