11 Facts About Sarcoidosis

1.

Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomata.

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2.

Sarcoidosis was first described in 1877 by the English doctor Jonathan Hutchinson as a non-painful skin disease.

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3.

Sarcoidosis is accompanied by psychological distress and symptoms of anxiety and depression, which are associated with fatigue.

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4.

Sarcoidosis'stologically, sarcoidosis of the heart is an active granulomatous inflammation surrounded by reactive oedema.

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5.

Sarcoidosis has paradoxical effects on inflammatory processes; it is characterized by increased macrophage and CD4 helper T-cell activation, resulting in accelerated inflammation, but immune response to antigen challenges such as tuberculin is suppressed.

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6.

Sarcoidosis is characterized by the formation of non-necrotizing granulomas in various organs and tissues.

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7.

Sarcoidosis is confused most commonly with neoplastic diseases, such as lymphoma, or with disorders characterized by a mononuclear cell granulomatous inflammatory process, such as the mycobacterial and fungal disorders.

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8.

Sarcoidosis occurs throughout the world in all races with an average incidence of 16.

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9.

Sarcoidosis is less commonly reported in South America, Spain, India, Canada, and the Philippines.

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10.

World Association of Sarcoidosis and Other Granulomatous Disorders is an organisation of physicians involved in the diagnosis and treatment of sarcoidosis and related conditions.

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11.

Additionally, the Foundation for Sarcoidosis Research is devoted to supporting research into sarcoidosis and its possible treatments.

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