Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant .
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13 Facts About Warfarin
2.
Warfarin first came into large-scale commercial use in 1948 as a rat poison.
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3.
Warfarin was formally approved for human use by the U S Food and Drug Administration to treat blood clots in 1954.
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4.
Warfarin is used to decrease the tendency for thrombosis, or as secondary prophylaxis in those individuals who have already formed a blood clot .
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5.
Warfarin is best suited for anticoagulation in areas of slowly running blood, and in blood pooled in dysfunctional cardiac atria.
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6.
Warfarin is usually best avoided in people with protein C or protein S deficiency, as these thrombophilic conditions increase the risk of skin necrosis, which is a rare but serious side effect associated with warfarin.
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7.
Warfarin is slower-acting than the common anticoagulant heparin, though it has a number of advantages.
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8.
Warfarin has a long half-life and need only be given once a day.
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9.
Warfarin was first registered for use as a rodenticide in the US in 1948, and was immediately popular.
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10.
Warfarin is tasteless and colourless, and produces symptoms similar to those that Stalin exhibited.
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11.
Warfarin is both odorless and tasteless, and is effective when mixed with food bait, because the rodents will return to the bait and continue to feed over a period of days until a lethal dose is accumulated .
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12.
Warfarin is used to cull vampire bat populations in areas where human–wildlife conflict is a concern.
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13.
Warfarin is a derivative of dicoumarol, an anticoagulant originally discovered in spoiled sweet clover.
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