19 Facts About Actelion

1.

Actelion is a pharmaceuticals and biotechnology company established in December 1997, headquartered in Allschwil near Basel, Switzerland.

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2.

Actelion focuses on the manufacture of drugs that treat rare diseases and orphan diseases.

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3.

One of the focuses of Actelion is treating individuals with pulmonary arterial hypertension, a heart condition that leaves patients with a short life expectancy even with treatment.

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4.

Actelion scientists were among the first to work in the field of endothelian receptor antagonists.

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5.

Actelion was initially financed with venture capital provided through a syndicate including Atlas Venture, Sofinnova and HealthCap.

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6.

Actelion develops and sells drugs in the continents of Asia, Europe and North and South America.

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7.

Actelion has 29 operative affiliates around the world, including in the United States, Canada, Brazil, Australia, Japan, Switzerland and a number of EU countries.

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8.

Actelion was founded in 1997 by husband and wife team Jean-Paul and Martine Clozel together with three colleagues after F Hoffmann-La Roche cut their funding for Martine's cardiovascular program.

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9.

In November 2006, CoTherix and Actelion signed a merger plan, which was announced publicly; this followed the initiation of negotiations in August 2006.

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10.

In January 2007, Actelion completed acquisition of all CoTherix stock, and summarily informed Asahi that work on fasudil would be terminated.

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11.

Now, Actelion had a competitor blockbuster drug on the market, bosentan .

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12.

Actelion was able to do this by illegally providing money to Medicare patients in order for them to be able to fulfill their co-payments for the drug Tracleer.

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13.

Actelion was able to use the charity organization by the name of Caring Voice Coalition to send money only to those people who were receiving prescriptions of Tracleer.

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14.

Actelion was complicit in referring patients to Caring Voice Coalition.

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15.

Actelion has been reported to start working with Analytics 4 Life to use imaging technology with regards to pulmonary hypertension.

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16.

Actelion currently has 10 compounds in its pipeline – including 3 in late-stage development – and 4 medicines on the market for orphan diseases:.

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17.

Actelion's shares have been listed on the SIX Swiss Exchange since 2000 SWX Swiss Exchange Swiss Leader Index.

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18.

In September 2008, Actelion shares began trading as part of the Swiss Market Index.

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19.

Actelion received the "Prix Hermes de l'innovation" in April 2011: The "European Institute for Creative Strategy and Innovation", the creator of the Prix Hermes, was founded in 2003 in France.

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