19 Facts About Fentanyl

Fentanyl, spelled fentanil, is a potent synthetic opioid used as a pain medication.

Fentanyl is commonly used to create counterfeit pills disguised as OxyContin, Xanax, Adderall, among others.

Fentanyl was first made by Paul Janssen in 1960 and approved for medical use in the United States in 1968.

Fentanyl is sometimes given intrathecally as part of spinal anesthesia or epidurally for epidural anaesthesia and analgesia.

Fentanyl is a highly lipophilic compound, which is well absorbed sublingually and generally well tolerated.

Related searches

Fentanyl can be used for patients in whom morphine is not tolerated, or whose breathlessness is refractory to morphine.

Fentanyl is especially useful for concomitant treatment in palliative care settings where pain and shortness of breath are severe and need to be treated with high strength opioids.

Fentanyl patient-controlled transdermal system is under development, which aims to allow patients to control administration of fentanyl through the skin to treat postoperative pain.

Fentanyl poses an exceptionally high overdose risk in humans, due to having an extremely unpredictable fatal dosage when mixed with other drugs.

Fentanyl has started to make its way into heroin as well as illicitly manufactured opioids and benzodiazepines.

Fentanyl was often produced in China and exported illegally to the U S The UK illicit drug market is no longer reliant on China, as domestic fentanyl production is replacing imports.

Fentanyl is a synthetic opioid in the phenylpiperidine family, which includes sufentanil, alfentanil, remifentanil, and carfentanil.

Fentanyl can produce the following clinical effects strongly, through µ-receptor agonism.

Fentanyl was first synthesized in Belgium by Paul Janssen under the label of his relatively newly formed Janssen Pharmaceutica in 1959.

Fentanyl citrate entered medical use as a general anaesthetic in 1968, manufactured by McNeil Laboratories under the trade name Sublimaze.

Fentanyl has a US DEA ACSCN of 9801 and a 2013 annual aggregate manufacturing quota of 2, 108.

Fentanyl is sometimes sold as heroin or oxycodone, sometimes leading to overdoses.

Fentanyl is sometimes sold on the black market in the form of transdermal fentanyl patches such as Duragesic, diverted from legitimate medical supplies.

Fentanyl has been discovered for sale in illicit markets in Australia in 2017 and in New Zealand in 2018.