Guanfacine, sold under the brand name Tenex among others, is an oral medication used to treat attention deficit hyperactivity disorder and high blood pressure.
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12 Facts About Guanfacine
2.
Guanfacine is FDA-approved for monotherapy treatment of ADHD as well as being used for augmentation of other treatments, such as stimulants.
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3.
Guanfacine is used off-label to treat tic disorders, anxiety disorders and PTSD.
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5.
Guanfacine is FDA approved as monotherapy or augmentation with stimulants to treat attention deficit hyperactivity disorder.
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6.
Guanfacine can offer a synergistic enhancement of stimulant treatment for ADHD, and in many cases can help control the side effect profile of stimulant medications.
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8.
Guanfacine appears to be especially helpful in treating children who have been traumatized or abused.
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9.
Guanfacine availability is significantly affected by the CYP3A4 and CYP3A5 enzymes.
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10.
Guanfacine is a highly selective agonist of the a2A adrenergic receptor, with low affinity for other receptors.
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11.
Guanfacine has been studied as a treatment for post-traumatic stress disorder.
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12.
Guanfacine has been investigated for treatment of withdrawal for opioids, ethanol, and nicotine.
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