Oxandrolone, sold under the brand names Oxandrin and Anavar, among others, is an androgen and anabolic steroid medication which is used to help promote weight gain in various situations, to help offset protein catabolism caused by long-term corticosteroid therapy, to support recovery from severe burns, to treat bone pain associated with osteoporosis, to aid in the development of girls with Turner syndrome, and for other indications.
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Oxandrolone was first described in 1962 and was introduced for medical use in 1964.
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Oxandrolone has been researched and prescribed as a treatment for a wide variety of conditions.
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Oxandrolone improves both short-term and long-term outcomes in people recovering from severe burns and is well-established as a safe treatment for this indication.
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Oxandrolone has, therefore, largely been replaced by growth hormone for this use.
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Oxandrolone can reduce males' fertility, another side effect common among androgens.
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Oxandrolone is the only AAS that is not primarily or extensively metabolized by the liver, and this is thought to be related to its diminished hepatotoxicity relative to other AASs.
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Oxandrolone is a synthetic androstane steroid and a 17a-alkylated derivative of DHT.
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Oxandrolone was first made by Raphael Pappo and Christopher J Jung while at Searle Laboratories .
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Oxandrolone is the generic name of the drug and its INN, USAN, USP, BAN, DCF, DCIT, and JAN, while ossandrolone is or was formerly the DCIT.
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Oxandrolone has been sold under the brand names Antitriol, Anatrophill, Lipidex, Lonavar, Protivar, and Vasorome, among others.
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Oxandrolone is one of the few AASs that remains available for medical use in the United States.
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