Mother Brain is a fictional character created by Nintendo for the Metroid series.
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Mother Brain is one of the most prominent antagonists within the series, serving as the main antagonist of Metroid and Super Metroid.
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Mother Brain has been killed multiple times by series protagonist Samus Aran.
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Mother Brain has made several appearances in other media, most notably as the primary antagonist in Captain N: The Game Master.
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Mother Brain is depicted as a very large brain with cybernetic spikes, usually contained in a glass tube which Samus must break to attack it.
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Mother Brain first appeared in the NES video game, Metroid, and again in the third Metroid title, Super Metroid.
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Mother Brain would appear again in the Game Boy Advance video game Metroid: Zero Mission, a remake of the NES Metroid, which explains what happens after Mother Brain's defeat.
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In Metroid: Other M, the scene of Mother Brain destroying the baby Metroid is reenacted in an FMV cutscene.
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Mother Brain makes multiple appearances in other media, most notably in Captain N: The Game Master, where she serves as the series' primary antagonist.
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Mother Brain ranked in as the ninth-best video game villain by IGN, stating that it would win an ugly contest "hands down".
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Mother Brain placed seventh on a reader poll conducted by GameSpot.
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Mother Brain is featured in the ongoing GameSpot's all-time greatest game villain.
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