Quinine is a medication used to treat malaria and babesiosis.
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19 Facts About Quinine
2.
Quinine is used as an ingredient in tonic water to impart a bitter taste.
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3.
Quinine was first isolated in 1820 from the bark of a cinchona tree, which is native to Peru, and its molecular formula was determined by Strecker in 1854.
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4.
Quinine was frequently prescribed as an off-label treatment for leg cramps at night, but this has become less common due to a warning from the US Food and Drug Administration that such practice is associated with life-threatening side effects.
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5.
Quinine can act as a competitive inhibitor of monoamine oxidase, an enzyme that removes neurotransmitters from the brain.
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6.
Quinine is a basic amine and is usually provided as a salt.
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7.
Quinine is a flavor component of tonic water and bitter lemon drink mixers.
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8.
Quinine are used as the chiral moiety for the ligands used in Sharpless asymmetric dihydroxylation as well as for numerous other chiral catalyst backbones.
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9.
Quinine has diverse unwanted interactions with numerous prescription drugs, such as potentiating the anticoagulant effects of warfarin.
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10.
Quinine is used for its toxicity to the malarial pathogen, Plasmodium falciparum, by interfering with its ability to dissolve and metabolize hemoglobin.
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12.
Quinine has been used in unextracted form by Europeans since at least the early 17th century.
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13.
Quinine played a significant role in the colonization of Africa by Europeans.
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14.
Quinine remained the antimalarial drug of choice until after World War II.
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15.
Bromo Quinine were brand name cold tablets containing quinine, manufactured by Grove Laboratories.
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16.
Quinine manufactured and sold "Dr Sappington's Anti-Fever Pills" across Missouri.
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17.
Quinine is approved for treatment of malaria, but was commonly prescribed to treat leg cramps and similar conditions.
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18.
Quinine is sometimes detected as a cutting agent in street drugs such as cocaine and heroin.
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19.
Quinine is used as a treatment for Cryptocaryon irritans infection of marine aquarium fish.
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